I do simple jobs on my own, like painting my shed, but for anything large or complicated, it just isn't worth the stress.
We've had Do Right painting perform three complex paint jobs, one which involved removal of a large amount of wallpaper and one which required custom cutting of complex drywall shapes to align with our poorly laid-out plumbing, and every time I was so happy that I had a professional do the work rather than attempting it myself, especially since their rates are usually very good. Sometimes you can even get a discount for work done in the winter, when they aren't booked.
They just finished the trim around my stained glass/front door (our fourth time with the company) and it looks fantastic, even though the wood was in bad shape. Will hire again for sure.